Archive of past meetings and training schools

Oxygen is increasingly recognized as a critical regulator of many biological processes at the molecular, cellular and tissue levels. Imbalances in its supply and/or consumption are linked with many pathological situations. Among others, brain and heart ischemia-related diseases and cancer progression are particularly linked with perturbed oxygen signalling and metabolism. The proposed conference is intended to cover all important aspects of the oxygen involvement in biochemical and molecular pathways, cell behavior, development, tissue functioning, and diseases. The satellite symposium “Oxygen in Health and Disease” offers an exciting scientific program and we look forward to your participation.

When oxygen availability is reduced, inherent physiologic responses are initiated through both cellular as well as systemic mechanisms. Hypoxia plays a crucial role in almost all acute and chronic diseases including, but not limited to, kidney and liver diseases, pulmonary hypertension, most forms of cardiovascular disease, retinal degeneration, wound healing, CNS pathologies, ischemia, inflammation, transplantation, acute or chronic mountain sickness and cancer. The Dublin Working Group meeting is dedicated to discussing and presenting the latest research in relation to “Therapeutic aspects of Hypoxia-inducible pathways”. This two day meeting will have four sessions dealing with Basic Science, Technology, Pharmacology and Translational Medicine of this hot topic in Hypoxia research.

When oxygen availability is reduced, inherent physiologic responses are initiated through both cellular as well as systemic mechanisms. Hypoxia plays a crucial role in almost all acute and chronic diseases including, but not limited to, kidney and liver diseases, pulmonary hypertension, most forms of cardiovascular disease including atherosclerosis, stroke, ischemic diseases, retinal degeneration, wound healing, several pathologies of the CNS, inflammation, transplantation, acute or chronic mountain sickness and - last but not least- tumorigenesis. OXYGEN 2011 brings together basic researchers working in the field of molecular hypoxia with their colleagues examining the hypoxic response in human volunteers and patients.

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How do we cope with reduced oxygenation (hypoxia)? While hypoxic conditions occurring at high altitude lead to acclimatization processes, more severe conditions require intense responses to minimize tissue damage. Once again, our Monte Verità meeting will emphasize the importance of linking molecular aspects of hypoxia to relevant physiological and pathological aspects of human medicine. Distinguished speakers will give us an overview of the current knowledge in the field and highlight new discoveries. Moreover, in two consensus sessions an expert panel will present and discuss aspects on high altitude pulmonary edema (HAPE) and doping in elite climbers. Special emphasis is also given to the emerging role of hypoxia in inflammatory and degenerative disorders.

 Note that this is a small meeting limited to a maximum of 100 participants (including speakers) that will allow intensive discussions.